Established Collaborative Research Programs

Performed first AAV (adeno-associated virus) gene transfer into the human brain in a FDA approved clinical trial.

Gene therapy approaches to Parkinson’s Disease, introducing genes encoding neurotransmitter biosynthetic enzymes and neurotrophic factors into the CNS.

Development of novel instrumentation and navigation systems for spinal surgery.

Gene therapy for pituitary adenomas and malignant brain tumors.

Analysis of polymeric and liposomal drug delivery devices for application to Neurosurgical and Spine disorders.

Gene and Cellular Therapy of Spinal Degenerative Disease.

Gene therapy of neurometabolic diseases (including Canavan Disease).

Clinical and radiological evaluation of spinal instrumentation and fusion procedures.