Abstracts

Freese, A., O’Connor, M.J., Leone, P., Ness, D.J., Xie, H., During, M.J. (1998): Genetic Intervention in an Animal Model of Epilepsy: Effects of Transfer of Genes Encoding Glutamic Acid Decarboxylase, a GABA Receptor Subunit, or Glial Cell-derived Neurotrophic Factor.  Annual Meeting of the American Association of Neurological Surgeons, Abstract 1263.

Freese, A., Young, D.D., Silver, D., Liu, C.Y., Davidson, B.L., O’Connor, M.J., Leone, P., During, M.J. (1998): Correlation Between Number of Transduced Cells and Behavioral Recovery in a Rat Parkinson’s Disease Model Following In Vivo Gene Therapy.  Annual Meeting of the American Association of Neurological Surgeons, Abstract 825.

During, M.J., Freese, A., Sorgi, F.L., Huang, L., Bilaniuk, L., Wang, Z., Mayes, L.C., Seashore, M.R., Mee, E., Leone, P. (1998): Intraventricular Delivery for Gene Therapy in the Fatal, Pediatric Neurogenetic Disorder, Canavan Disease.  Annual Meeting of the American Association of Neurological Surgeons, Abstract 821.

During, M.J., Freese, A., Woodgate, A.M., Lipski, J., Young, D., Xu, R. (1998): Transfer of the c-Jun Gene into PC12 Cells Induces Differentiation into a Neuronal-like Phenotype. Annual Meeting of the American Association of Neurological Surgeons, Abstract 1351.

During, M.J., Dragunow, M., Woodgate, A.M., Xu, R., Freese, A. (1998): The Phosphorylated State of c-Jun Following Okadaic Acid Induced Apoptosis and Nerve Growth Factor-Induced Sprouting in PC12 Cells.  Annual Meeting of the American Association of Neurological Surgeons, Abstract 1143.

Simeone, F.A., Freese, A. (1998): The opportunity costs of training to become a neuro-surgeon: relevance for the expectation of appropriate compensation.  Annual Meeting of the American Association of Neurological Surgeons, Abstract 726.

Freese, A. (1998): Prospects of Gene therapy Approaches to Neuromodulation.  4th International Congress of the International Neuromodulation Society.

Leone, P., Duncan, C., Barolat, G., Freese, A., Seashore, M., Sorge, F., Cherniske, E., Janson, C.G., During, M.J. (1998): Gene Therapy of Canavan Disease uisng LPD/pAAV-ASPA: A Phase 1 Study. Proceedings 28th Annual Meeting, Society for Neuroscience, Abstract 405.4.

Simeone, F.A., Freese, A. (1999):  The Devaluation of Neurosurgical Procedures by Managed Care and the Relevance of the Consumer Price Index over the Past Decade.         Annual Meeting of the American Association of Neurological Surgeons, Abstract 752.

Abbey, M.V., Freese, A., Bagasra, O., O’Connor, W.M., Memoli, M., Van Bockstaele, E., O’Connor, M.J. (1999):  In Situ rtPCR: A Novel Approach towards Evaluating Gene Expression in Human Brain Tissue.  Annual Meeting of the American Association of Neurological Surgeons, Abstract 1352.

McPhee, S.J., Fenu.S., Xu, R., Mastakov, M., Fan, X, Freese, A., During, M.J., Leone, P. (1999): In Vivo Analysis of Tyrosine Hydroxylase Expression Cassettes in the 6-OHDA Parkinsonian Rat Model Using AAV Vectors: A Repeated Injection Paradigm. Proceedings 2nd Annual Meeting of the American Society of Gene Therapy Abstract 200.

Harrop, J., Poulsen, D.J., Maragakis, N.J., Xiao, W., Liu, Y., Luo, J., Rothstein, J.D., Freese, A., During, M.J. (2000): Transduction of Neurons and Astrocytes within the Rat Spinal Cord using Recombinant AAV-2 and Pseudotyped AAV-5. Proceedings 30th Annual Meeting, Society for Neuroscience, Abstract 259.7

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